Knob Lick is an unincorporated community in southern Saint Francois County, Missouri. It is located on U.S. Route 67 about eight miles south of Farmington. Knob Lick has a post office with zip code 63651.[1]
The community was named in 1876 for the nearby Knob Lick Mountain. In the Ozarks, knob typically refers to an isolated summit, and lick is a natural "salt lick" or salt spring. The mountain is across U.S. Route 67 from the town at . Eighty 80 acres (32 ha) of the summit are protected by the Missouri Department of Conservation. A gravel road leads to the conservation area which includes a granite glade, picnic facilities, and a closed fire lookout tower.[2]
The St Louis and Iron Mountain Railroad had a stop at Knob Lick that was a shipping point for granite mines in the area. There were also lead mines nearby, including Mine La Motte. Knob Lick has been home to the S-F Scout Ranch since 1965.
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